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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH2D2A
All Species:
11.82
Human Site:
S339
Identified Species:
43.33
UniProt:
Q9NP31
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP31
NP_001154913.1
389
42934
S339
G
G
Q
N
T
G
G
S
Q
L
H
S
E
N
S
Chimpanzee
Pan troglodytes
XP_001167540
389
43049
S339
G
G
Q
N
T
G
G
S
Q
L
H
S
E
N
S
Rhesus Macaque
Macaca mulatta
XP_001116816
389
42792
S339
G
G
Q
N
T
G
G
S
Q
L
H
S
E
N
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXK9
374
40935
T334
E
V
E
G
P
S
G
T
A
P
I
G
H
P
I
Rat
Rattus norvegicus
NP_997488
376
41319
G340
P
R
E
M
L
P
I
G
H
P
T
L
H
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P13116
532
59718
S442
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
Zebra Danio
Brachydanio rerio
XP_698916
524
58529
I438
H
E
Y
S
E
V
N
I
K
G
A
Q
E
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
93.5
N.A.
N.A.
62.7
61.7
N.A.
N.A.
N.A.
20.4
25.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
94.5
N.A.
N.A.
71.2
69.9
N.A.
N.A.
N.A.
35.3
39.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
20
6.6
N.A.
N.A.
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% D
% Glu:
15
15
29
0
15
0
0
0
0
0
0
0
58
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
43
58
0
15
0
43
58
15
0
15
0
15
0
29
0
% G
% His:
15
0
0
0
0
0
0
0
15
0
43
0
29
0
0
% H
% Ile:
0
0
0
0
0
15
15
15
0
0
15
0
0
0
29
% I
% Lys:
0
0
0
0
0
0
15
0
15
0
0
0
0
15
0
% K
% Leu:
0
0
0
0
15
0
0
0
0
43
0
15
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
43
0
0
15
0
0
0
0
0
0
43
15
% N
% Pro:
15
0
0
0
15
15
0
0
0
29
0
0
0
15
0
% P
% Gln:
0
0
43
0
0
0
0
0
43
0
0
15
0
0
0
% Q
% Arg:
0
15
15
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
15
0
58
0
0
0
58
0
0
43
% S
% Thr:
0
0
0
0
58
0
0
15
0
0
15
0
0
0
0
% T
% Val:
0
15
0
0
0
15
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
15
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _